Innovax-ILT (Cell-associated live recombinant turkey...) - QI01AD03
Updated on site: 09-Feb-2018
|Substance:||Cell-associated live recombinant turkey herpesvirus (strain HVT/ILT-138), expressing the glycoproteins gD and gI of infectious laryngotracheitis virus|
|Manufacturer:||Intervet International B.V.|
Avian infectious laryngotracheitis and Marek’s disease vaccine (live recombinant)
This is a summary of the European public assessment report (EPAR) for
For practical information about using
ILT is an infection of the airways which may affect growth and decrease egg production in chickens. The disease is caused by a herpesvirus and can be mild (causing watery eyes, nasal discharge and mild inflammation of the windpipe) or severe, causing dyspnoea (difficulty breathing), respiratory depression and coughing up of blood.
MD is another herpesvirus infection of chickens which can cause paralysis of the wings and legs and causes tumours in various organs. Chickens become infected at an early age via inhalation of dander (flakes of skin) containing the virus which can remain infectious for several months after being shed from the body. Birds infected with MD virus can be carriers and shedders of the virus for life.
injection under the skin in the neck. Protection against ILT starts 4 weeks after vaccination and lasts 60 weeks. Protection against MD starts 9 days after vaccination and lasts for life.
What benefits of
A field trial in chickens was performed to evaluate the effects of the vaccine against ILT and MD. Mortality was low, no disease related signs were observed and the condition of the chickens was good throughout the trial, indicating effectiveness of the vaccine.
Chickens were taken from the field trial and challenged (exposed to infection) in the laboratory to demonstrate protection after vaccination. To evaluate the effects of the vaccine against MD, chickens vaccinated either with
In a second challenge study the effectiveness of the vaccination with
What are the risks associated with
There are no known side effects. For the full list of restrictions, see the package leaflet.
What are the precautions for the person who gives the medicine or comes into contact with the animal?
Safety information has been included in the summary of product characteristics and the package leaflet for
As the vaccine is stored in liquid nitrogen, it is important that any handling is done in a
What is the withdrawal period in
The withdrawal period is the time required after administration of a medicine before an animal can be slaughtered and the meat used for human consumption. It is also the time required after administration of a medicine before eggs may be used for human consumption.
The withdrawal period for meat and eggs from chickens treated with
The Agency’s Committee for Medicinal Products for Veterinary Use (CVMP) concluded that Innovax- ILT’s benefits are greater than its risks and recommended that it be approved for use in the EU.
Other information about
The European Commission granted a marketing authorisation valid throughout the EU for
The full EPAR for
This summary was last updated in May 2015.